Direct numerical simulation is used to investigate effects of heat release and compressibility on mixing-layer turbulence during a period of self-similarity. Temporally evolving mixing layers are analysed at convective Mach numbers between 0.15 and 1.1 and in a Reynolds number range of 15000 to 35000 based on vorticity thickness. The turbulence inhibiting effects of heat release are traced back to mean density variations using an analysis of the fluctuating pressure field based on a Green's function.